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Klippel-Trenaunay syndrome is a rare, congenital condition that causes a red and purple colored birthmark, vein malformation, or soft tissue growth to develop on a limb. The affected limb may also be larger, longer, or warmer than usual. Despite all of these symptoms, the most notable sign of Klippel-Trenaunay syndrome is the red and purple colored port-wine stain. According to the U.S. National Library of Medicine, Klippel-Trenaunay syndrome affects approximately 1 in 100,000 people worldwide.


Symptoms of Klippel-Trenaunay syndrome vary depending on the severity of the condition’s malformation. Patients may experience the following:

  • Bleeding from the affected limb
  • Pain or mild discomfort near the malformation
  • Skin infections
  • Blood clots
  • Anemia

If you are experiencing Klippel-Trenaunay Syndrome symptoms, it may be time for a professional review.

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